Biological Electron Microscopy (EM) Core Facility
The Biological Electron Microscopy (EM) Core Facility is administered and supported by the Institute of Cellular and Organismic Biology and the AS Core Facility and Innovative Instrument Project. Its goal is to provide researchers with technical consultation and operational training for EM sample preparation, with services available to researchers both at and outside AS. This facility is equipped with one transmission electron microscope, as well as equipment for carrying out sample processing for imaging from tissue to molecular levels.
Location: EM Room, 1F, Institute of Cellular and Organismic Biology
Manager: Dr. Po-Yen Lin, Assistant Research Scientist, Institute of Cellular and Organismic Biology
Contact Person: Mr. Yao-Kwan Huang, Ms. Dia-Nan Lin and Ms. Yan-An Lin
Phone Number: 2787-1534
Website: https://image-core.icob.sinica.edu.tw/pages/3788
Availability: Services available to Academia Sinica faculty members and their associates, as well as research institutes and biotech companies outside AS.
Services: We support various sample preparations (cells, tissues, and synthetic soft materials), including negative stains, heavy metal shadowing, conventional resin embedding/sectioning, high pressure freezes, and freeze-substitution embedding/sectioning.
Equipment:
- FEI Tecnai G2 F20 S-Twin Electron Microscope
- Microwave Sample Processor
- High pressure freeze HPM101 and Freeze-substitution systems, Leica EM AFS 2
- Vacuum Evaporator and Glow Discharge System
- Ultramicrotome micro-dissection equipment