Proteomics Mass Spectrometry Common Facility
The Academia Sinica Mass Spectrometry Common Facilities for Proteomics and Protein Modification Analysis, located on the 4th floor of the Institute of Biological Chemistry, includes a fleet of hybrid and Tribrid Orbitrap instruments configured primarily for advanced nanoLC-nanoESI-MS/MS analyses. The Thermo LTQ-Orbitrap Velos and Elite systems are used for routine proteomic ID and initial screen analysis on less complex samples, while high end equipment Orbitrap Fusion and Lumos systems are for advanced quantitative shotgun proteomics, PTMomics, glycoproteomics and glycomics. These facilities further house a Waters Synapt G2 HDMS configured with a fully automated hydrogen-deuterium exchange (HDX) system for protein structure and conformation analysis. Facility users applying for the first time are strongly advised to contact the Manager to discuss research needs and workflow design from sample preparation to data analysis. Training courses, seminars, and lectures are also offered to prospective users.
Location: Room 401, 4F, Institute of Biological Chemistry.
Manager: Dr. Shu-Yu Lin, Associate Research Specialist, Institute of Biological Chemistry
Contact Person: Dr. Shu-Yu Lin, Associate Research Specialist, Institute of Biological Chemistry
Phone Number: 2785-5696 ext. 4012 or 4017
Website: https://sites.google.com/view/ascmsf/
Availability: Services available to Academia Sinica faculty members and their associates, as well as research institutes and biotech companies outside AS.
Services:
- Simple/complex protein identification, post-translational modifications (PTM) analysis, and full scale quantitative shotgun proteomics applications
- Training courses on theories, sample preparation, and data analysis
Equipment:
- Thermo LTQ-Orbitrap Velos Mass Spectrometer
- Thermo LTQ-Orbitrap Elite Mass Spectrometer
- Thermo Orbitrap Fusion Tribrid Mass Spectrometer
- Thermo Orbitrap Fusion Lumos Tribrid Mass Spectrometer
- Waters Synapt G2 High Definition Mass Spectrometer
Proteomics Mass Spectrometry Common Facility