Academia Sinica Protein Clinic
Academia Sinica Protein Clinic (ASPC) is a service provider for integrated and multiplex structural biology and biophysics with know-how, streamlined workflow, and data analysis. ASPC provides initial consultations to assist users in obtaining recombinant protein sample and to design workflows for biophysical and structural characterizations. Reminiscent to health checkups, ASPC provides basic and advanced diagnosis packages or individual items to obtain an overview about the target protein system, which that can be seamlessly interfaced with more advanced structural and functional characterizations by other core-facilities (such as Biophysics Core Facility, Common Mass Spectrometry Core Facility and cryoEM) within Academia Sinica. ASPC provides routine crystallization screening trials, and, on a collaborative basis, more advanced physicochemical, structural and functional analyses.
Facility Location: Room 401, Institute of Biological Chemistry
Facility Manager: Dr. Shang-Te Danny Hsu, Research Fellow, Institute of Biological Chemistry
Contact Person: Dr. Yun-Ru Chen, Project Manager, Academia Sinica Protein Clinic, Institute of Biological Chemistry
Mr. Cheng-Wei Huang, Assistant, Academia Sinica Protein Clinic, Institute of Biological Chemistry
Ms. Jing-Siou Huang, Assistant, Academia Sinica Protein Clinic, Institute of Biological Chemistry
Ms. Chia-wei Cheng, Assistant, Academia Sinica Protein Clinic, Institute of Biological Chemistry
Phone Number: 2785-5696 #4010
Facility Website URL: https://aspc.ibc.sinica.edu.tw/index-E.php
Served Customers: Academia Sinica faculty users, non-AS academic institutes users, and industrial users
Service Items: Protein quality control service package
Instrument or Equipment Used:
- Protein QC Basic Package
- Protein QC Deluxe Package
- Protein QC size-exclusion coupled multiangle light scattering (SEC-MALS)
- Asymmetric field flow-coupled multiangle light scattering (AF4-MALS)
- Analytical size-exclusion chromatography (SEC)
- Circular dichroism (CD) spectrometer Jasco J815
- Differential scanning fluorimeter (DSF) by qPCR LightCycler 480 II
- UV/VIS spectrometer Jasco V630 Bio
Academia Sinica Protein Clinic