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- Histone H2B Ubiquitylation Slows DNA Replication and Promotes Genome Stability under Stress ...2014-11-12
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【Full Text】H2B Mono-ubiquitylation Facilitates Fork Stalling and Recovery during Replication Stress by Coordinating Rad53 Activation and Chromatin Assembly

PLoS Genetics, 2014

 

 
- Global Study Suggests that Low Birth Rate will not Hurt Standard of Living in Most Countries, but may in Taiwan ...2014-11-10
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【Full Text】Is low fertility really a problem? Population aging, dependency, and consumption

Science, 2014

 

 
- Genomic and Biosynthesis Pathway Analysis of Precious Taiwan Medicinal Mushroom Antrodia cinnamomea ...2014-11-06
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【Full Text】Genomic and transcriptomic analyses of the medicinal fungus Antrodia cinnamomea for its metabolite biosynthesis and sexual development

Proceedings of the National Academy of Sciences, 2014

 

 
- Elucidation of Structure of PTPN3-p38γ Complex Points to New Cancer Drug Design Strategy ...2014-10-31
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【Full Text】Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain–modulated complex formation

Science Signaling, 2014

 

 
- Crowning Proteins: Modulating the Protein Surface Properties Using Crown Ethers ...2014-10-16
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【Full Text】Crowning Proteins: Modulating the Protein Surface Properties using Crown Ethers

Angewandte Chemie, 2014

 

 
- Spherical TDP-43 Oligomers Likely Play a Key Role in the Mechanism of Neurodegenerative Diseases ...2014-09-16
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【Full Text】Full-length ​TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Nature Communications, 2014

 

 
- Discovery of Farthest Lensing Galaxy Yields Clues to Early Universe ...2014-07-24
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【Full Text】DISCOVERY OF A STRONG LENSING GALAXY EMBEDDED IN A CLUSTER AT z = 1.62

The Astrophysical Journal Letters, 2014

 

 
- Discovery of DNase Effectors as Weapons for Agrobacterium Survival Advantage during Plant Colonization ...2014-07-15
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【Full Text】Agrobacterium tumefaciens Deploys a Superfamily of Type VI Secretion DNase Effectors as Weapons for Interbacterial Competition In Planta

Cell Host & Microbe, 2014

 

 
- The Mechanisms of Anti-IgE Medication in Treating Chronic Spontaneous Urticaria ...2014-06-25
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【Full Text】The potential pharmacologic mechanisms of omalizumab in patients with chronic spontaneous urticaria

Journal of Allergy and Clinical Immunology, 2014

 

 
- Exploring a Parasitic Tunnel Boring Machine - The whipworm genome and dual-species transcriptomics of an intimate host-pathogen interaction ...2014-06-18
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【Full Text】Whipworm genome and dual-species transcriptome analyses provide molecular insights into an intimate host-parasite interaction

Nature Genetics, 2014

 

 
- Beetle Study Suggests Formation of Cooperative Societies May be Key to Success Amidst Climate Change Challenges ...2014-06-10
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【Full Text】Climate-mediated cooperation promotes niche expansion in burying beetles

eLife, 2014

 

 
- Biological Chemists discover that Lysine 33-linked Ubiquitin Chains Function in Protein Trafficking ...2014-04-28
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【Full Text】K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking

Molecular Cell, 2014

 

【PPT File】K33-linked Polyubiquitination of Coronin7 by Cul3-KLHL20 Ubiquitin E3 ligase Regulates Protein Trafficking

This study represents the first description of the cellular decoding mechanism and the first demonstration of a positive signaling (nondegradable) role of the K33-linked ubiquitin chain.

 
- Why Plant Stop Growing under Abiotic Stress? ...2014-04-22
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【Full Text】SnRK1A-Interacting Negative Regulators Modulate the Nutrient Starvation Signaling Sensor SnRK1 in Source-Sink Communication in Cereal Seedlings under Abiotic Stress

The Plant Cell, 2014

 

 
- Plant Biologists Discover that Lipids Control Flowering Time ...2014-04-08
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【Full Text】Arabidopsis florigen FT binds to diurnally oscillating phospholipids that accelerate flowering

Nature Communications, 2014

 

 
- Rules are Made to be Broken: Scientists Uncover how a Viral DNA Polymerase Breaks the Golden Watson-Crick Rule ...2014-03-31
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【Full Text】How a Low-Fidelity DNA Polymerase Chooses Non-Watson–Crick from Watson–Crick Incorporation

Journal of American Chemical Society, 2014

 

【PPT File】How a DNA Polymerase Breaks the Watson-Crick Rule

DNA polymerase X from African swine fever virus is able to bind MgdGTP specifically before binding DNA. This mechanism allows the enzyme to overcome Watson-Crick base pairing in order to catalyze G:G mismatch, and resolves a long standing mystery for low-fidelity DNA polymerases.

 
- RNase T in DNA repair ...2014-03-25
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【Full Text】Structural Insights Into DNA Repair by RNase T—An Exonuclease Processing 3′ End of Structured DNA in Repair Pathways

PLOS, 2014

 

 
- A Twist in the Twin-tail: the Molecular Development Underlying Goldfish Caudal Fin Morphology ...2014-03-24
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【Full Text】The origin of the bifurcated axial skeletal system in the twin-tail goldfish

Nature Communications, 2014

 

【PPT File】The origin of the bifurcated axial skeletal system in the twin-tail goldfish

Dr. Gembu Abe, with the support of colleagues in the laboratory of Dr. Kinya G. Ota (Marine Research Station, ICOB), has demonstrated that the twin tail of certain goldfish strains arises from a mutation in chordin, a gene related to dorsal-ventral patterning.

 
- A Novel Phosphorylation Event Activates Bacterial Type VI Secretion ...2014-03-24
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【Full Text】Fha Interaction with Phosphothreonine of TssL Activates Type VI Secretion in Agrobacterium tumefaciens

PLoS PATHOGENS, 2014

 

 
- Timed Nuclear Import of a Transcription Factor During Erythropoiesis ...2014-03-14
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【Full Text】Tight Regulation of a Timed Nuclear Import Wave of EKLF by PKCθ and FOE during Pro-E to Baso-E Transition

Developmental Cell, 2014

 

 
- Plant Biologists use Microgenomics to Overcome Hurdle in Pollination Study: Profile Translatome of Pollen Tubes Growing within the Flowe ...2014-02-26
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【Full Text】Profiling of Translatomes of in Vivo–Grown Pollen Tubes Reveals Genes with Roles in Micropylar Guidance during Pollination in Arabidopsis

The Plant Cell, 2014

 

【PPT File】Exploring the translatomes of in vivo pollen tubes reveals genes with unique roles in micropylar guidance during pollination

Microgenomics and genetic approaches were used to identify and explore the functions of pollen tube transcripts upregulated by pollination.

 
- Physicists Put another Piece in the Superconductivity Puzzle — Discovery of Fe-vacancy Orders in the FeSe system ...2014-02-18
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【Full Text】Fe-vacancy order and superconductivity in tetragonal β-Fe1-xSe

PNAS, 2014

 

 
- Aberrant Neural Circuits – A Cause and Potential Therapy for Autism Spectrum Disorders ...2014-01-29
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【Full Text】Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality

Nature Neuroscience, 2014

 

 
- Scientists Re-engineer Flu Vaccine to Provide Greater Protection against More Strains ...2014-01-28
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【Full Text】Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections

PNAS, 2014

 

【PPT File】Vaccination of Monoglycosylated Hemagglutinin induces Cross-strain Protection against Influenza Virus Infections

Monoglycosylated HA provides cross-strain protection against infection from various H1N1 viruses in mice and ferrets.

 
- Photoreceptors regulate light-responsive alternative splicing in plants ...2014-01-16
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【Full Text】Genome-wide analysis of light-regulated alternative splicing mediated by photoreceptors in Physcomitrella patens

Genome Biology, 2014

 

 
- Taiwan Scientists Identify a Gene that Can Predict Response to Lithium Therapy for Bipolar I Disorder in Han Chinese ...2014-01-15
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【Full Text】Variant GADL1 and Response to Lithium Therapy in Bipolar I Disorder

New England Journal of Medicine, 2014

 

 

 


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